The crude hydroalcoholic extract of Piper longum (Piperaceae) fruits were evaluated for in-vitro anthelmintic activity on the Indian adult earthworms Pheretima posthuma. The various concentrations (10,25,50mg/ml) of extract was tested in-vitro for anthelmintic potency by determination of time of paralysis and time of death of worm. The fruit extract of Piper longum exhibited a dose dependant inhibition of spontaneous motility (Paralysis) of earthworms. Albendazole (10mg/ml) is used as standard drug. The extract was found to be more potent than albendazole. Thus the present study demonstrates that the fruit of Piper longum could be categorized under anthelmintic herbal drugs and could be used as a potent key ingredient of herbal formulation.
Loading....